Bone Right bone health support aid 120 caps

Regular, weight-bearing exercise and a healthy diet with adequate calcium, including from Bone Right helps build bone mass and maintain bone health and may reduce their risk of osteoporosis later in life. Adequate calcium intake is also linked to reduced osteoporosis by slowing bone loss in older men and women. Bone Right offers the highest quality nutrient profile proven to support healthy bone growth and maintenance.

Microcrystalline Hydroxyapatite Concentrate (MCHC) is a highly bioavailable source of calcium and phosphorus, the mineral building blocks of bone. Several studies involving corticosteroid induced bone loss have shown that MCHC can significantly reduce the rate of bone loss. MCHC is the actual matrix that makes up much of the bones’ structure and provides over 45 whole bone proteins. Supplementing with MCHC provides calcium, phosphorus, and trace amounts of other minerals. As with Cissus, research has shown MCHC to be effective at limiting the bone loss associated with high levels of cortisol. For this reason it may be of particular interest to those subject to stress associated with physical training, or simply the stress of everyday life. Although alternate forms of calcium are available for supplementation, such as calcium carbonate, MCHC based calcium supplementation has been shown to have better effects on bone density than other forms of calcium.

Glucosamine is a aminomonosaccharide, consisting of a combination of glutamine and glucose. Glucosamine taken orally is concentrated in joint cartilage where the body uses it as a substrate for cartilage glucosaminoglycan synthesis. Reviews of the clinical trials and metaanalyses support the efficacy of glucosamine to support joint health.

Besides serving as a building block for articular cartilage, glucosamine has been shown to suppress the formation of the inflammatory compounds PGE and nitric oxide produced by immune cells (This is not to be confused with the nitric oxide produced by working muscles and NO supplements). The latter two act as vasodilators and are beneficial for blood and nutrient delivery to exercising muscle.)

Vitamin D is well known as a hormone involved in mineral metabolism and bone growth. Its best-known effect is to facilitate intestinal absorption of calcium, although it also stimulates absorption of phosphate and magnesium ions. In the absence of vitamin D, dietary calcium is not absorbed efficiently. Vitamin D stimulates the _expression of a number of proteins involved in transporting calcium from the interior (lumen) of the intestine, across the epithelial cells and into blood. The best studied of these calcium transporters is calbindin, an intracellular protein that shuttles calcium across the intestinal epithelial cell. Experts have shown concern that dietary levels of Vitamin D are insufficient to stave off osteoporosis in men and have recommended a minimum of 400 – 800 IU daily during adulthood to prevent the development of osteoporosis.*

MCHA (microcrystalline hydroxyapatite)
Calcium (from MCHA)

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